George is a kind-hearted kindergarten teacher who weighs nearly 700 pounds. He is determined to lose weight to help him win back his ex-girlfriend.
Plagued by health problems, Meghan hopes to get weight loss surgery along with her overweight best friend, Vanessa.
After a painful recovery from bariatric surgery, Meghan works hard to keep Vanessa's diet on track. But Vanessa is struggling to lose any weight.
A car accident led to Jennifer's weight gain and a massive leg lymphedema. She believes bariatric surgery is her last chance to regain mobility.
Jasmin knows that she must get bariatric surgery so she can take care of her mum, who was recently diagnosed with MS, and her 7-year-old son.
At 708 pounds, Jessica is battling a host of life-threatening illnesses, and an emergency hospitalisation throws her weight loss off track.