Jasmin knows that she must get bariatric surgery so she can take care of her mum, who was recently diagnosed with MS, and her 7-year-old son.
Plagued by health problems, Meghan hopes to get weight loss surgery along with her overweight best friend, Vanessa.
After a painful recovery from bariatric surgery, Meghan works hard to keep Vanessa's diet on track. But Vanessa is struggling to lose any weight.
George is a kind-hearted kindergarten teacher who weighs nearly 700 pounds. He is determined to lose weight to help him win back his ex-girlfriend.
A car accident led to Jennifer's weight gain and a massive leg lymphedema. She believes bariatric surgery is her last chance to regain mobility.
At 708 pounds, Jessica is battling a host of life-threatening illnesses, and an emergency hospitalisation throws her weight loss off track.